Leukemia cure standard

Patients with early onset of leukemia, in vivo there are 1011 ~ 1012 / L (l) leukemia cells, after treatment, leukemia cells could be decreased to 109 ~ 1010 / L, this time the general clinical symptoms had disappeared, hemogram, bone marrow, as has been restored to normal, said for clinical remission in clinical remission, there are three different standards to judge the degree of mitigation of leukemia therapy.

(A) Mitigation Standard

1. Complete remission:

(1) Bone marrow: The original granulocyte (I-+ II-type) or the original single + young + young single or pouring cream of the original cell count ' 5%, red blood cells and normal megakaryocyte cell lines. Which M2b neutral in promyelocytic cell ratio in the normal range; M3-type of the original grain + promyelocytic ' 5%; M4-type Zhongyuan grain-I + II + type + of the original single-child single-' 5%; M6-type Zhongyuan tablets I Type + II-type ' 5%, the original Red + Red, as well as erythroid ratio of young normal; M7 medium-grained, red two-line ratio of normal, the former Giant and young giant disappeared.

(2) blood as: hemoglobin (Hb) ' 100g (g) / L (men) or ' 90g / L (women and children), absolute neutrophils ' 1. 5xl09 / L, platelet count ' 100xl09 / L, No category leukemia cells.

(3) clinical manifestations: No infiltration of leukemia caused by the symptoms and signs, living normal or near normal.

2. Partial remission: bone marrow Zhongyuan granulocyte-I + II-type (or the original single + young + young single or pouring cream of the original)> 5%, ' 20%, or clinical, blood, as two have not reached a standard of complete remission persons.

3. Non-remission: bone marrow, blood and clinical as the three failed to meet the above standards.

(B) relapse

One of the three with the following recurrence:

1. In the original bone marrow granulocyte-I + II-type (or the original single + young + young single or pouring cream of the original)> 5%, ' 20%, after a course of anti-leukemia therapy still can not reach clinical remission.

2. Primitive bone marrow granulocyte-I + II-type (or the original single + young + young single or pouring cream of the original) "20% of those.

3. There extramedullary infiltration by leukemic cells.

(C) continuous complete remission

From treatment, was calculated from the date of clinical remission, during which no relapse up to 3 ~ 5 years or more commonly known.

(D) Long-term survival

Since the date of diagnosis of leukemia, the survival time (disease-free survival or disease) for up to 5 years as long-term survival. In which disease-free survival or leukemia-free survival period is defined from the clinical remission until relapse or until the death of a state of clinical remission time.

(E) clinical cure

Cessation of chemotherapy, disease-free survival of 5 years or 10 years shall be known as clinical cure.