Clinical features of type 1 diabetes mellitus

Type 1 diabetes is islet β-cells were due to severe damage caused. Features are: pancreatic islet β-cells are rapidly and severely damaged, leading to insulin rapidly, a serious lack.

Clinical features of type 1 diabetes: a serious lack of insulin, "more than three a little" is obvious. Disease is very sudden, very violent oncoming force. Most patients have a significant incidence of "more than three a little" symptoms. Like "overnight" islet β-cells, was completely destroyed. But a small number of patients may have a grace period of several months. That is, after several months of time, islet β-cells was only completely destroyed.

Etiology of type 1 diabetes: some with auto-immune related, some with certain virus infection. Some research suggests that breast milk-fed children than the children suffering from type 1 diabetes more chances, so promotion of breastfeeding. Some of the reasons also unknown, is still a not completely shrouded in mystery.

Adult late-onset autoimmune diabetes is a special type 1 diabetes.

1. Onset age for adults, more in 20-50 years, and mostly normal-weight or low body weight.

2. Pathogenesis of early stage and type 2 diabetes is similar, but also an effective oral hypoglycemic agents. However, after a period of time, oral hypoglycemic agents failure, increasing blood sugar, symptoms become increasingly obvious that the blood levels of insulin, C-peptide levels gradually decreased. The indicators can meet the following criteria:

' 1 fasting blood glucose ' 16.5mmol / L

' 2 fasting plasma C-peptide values of <0.4mmol / L, oral glucose, plasma C-peptide values after the <0.8mmol / L

' 3 body mass index ' 25

3. Glutamic acid decarboxylase antibodies.

4. Genetic test: HLA-DQB1 chain of the first 57 points, a non-aspartic acid homozygous gene.

Among them, (1) ~ (2) the basic conditions for the diagnosis, coupled with (3) or (4), one can be diagnosed with late-onset autoimmune diabetes in adults.